The Basics
How Wrinkle Relaxers Work
All four brands use botulinum toxin type A as their active ingredient. When injected in small, precise doses, the toxin temporarily blocks the nerve signals that tell a targeted muscle to contract. With the muscle relaxed, the skin above it smooths out — without affecting surrounding muscles or your ability to make natural expressions when treatment is done well.
Results are temporary. The nerve signals gradually return over months, and muscle activity — along with the lines it creates — begins to come back. Regular maintenance keeps results consistent. The mechanism is identical across all four brands; what differs is how each company formulates, stabilizes, and delivers the toxin.
What all four brands share
FDA-approved for cosmetic use
Botulinum toxin type A active ingredient
Same treatment areas
Minimal downtime — return to activities same day
Results appear within days
Temporary — results last months, not permanently
Adjustable at follow-up
Can be combined with other treatments
Common treatment areas
Forehead lines
Most common
Frown lines ("11s")
Between the brows
Crow's feet
Around the eyes
Lip flip
Upper lip rollout
Brow lift
Subtle arch elevation
Bunny lines
Bridge of the nose
Jawline slimming
Masseter reduction
Neck bands
Platysma bands
Chin dimpling
"Orange peel" texture
Hyperhidrosis
Botox FDA-approved
Treatment areas available at both RELUXE locations — Westfield and Carmel. Your injector determines which areas are appropriate for your anatomy and goals.
Brand Breakdown
The Four Options at RELUXE
Each brand below has its own clinical history and characteristics that make it a strong choice for the right patient. No brand is ranked above another — these are four genuinely good options. Your injector will help you find the right fit.
Botox
The most studied neurotoxin, with 20+ years of clinical history
Onset
3–7 days
Duration
Typically 3–4 months
Spread
Precise, targeted
Loyalty
Allē Rewards
Pricing at RELUXE
$280 Foundation (20 units)
$9/unit new patient · $10/unit returning
Botox has the longest clinical track record of any aesthetic neurotoxin — over two decades of data across millions of treatments. It is known for precise, predictable placement and has been the benchmark that other brands are measured against. Beyond cosmetic use, Botox holds additional FDA approvals for chronic migraine prevention and primary hyperhidrosis (excessive sweating), which speaks to the depth of its clinical research.
Notable for
- 20+ years of safety and efficacy data
- Precise, targeted muscle relaxation
- Additional FDA approvals for medical conditions
- Allē Rewards loyalty program by Allergan
Some patients prefer this if
You have used Botox before and have a consistent relationship with your results. Or if you want the brand with the longest clinical history and the broadest body of research behind it.
Dysport
Known for broader diffusion — popular for larger treatment areas
Onset
2–5 days
Duration
Typically 3–4 months
Spread
Slightly broader diffusion
Loyalty
Galderma Aspire
Pricing at RELUXE
$4.00–$4.50 per unit
$4.00/unit for members · Higher unit count per area
Dysport has a slightly broader diffusion pattern than some other neurotoxins, which makes it a preferred option for treating larger, flatter muscle groups — particularly the forehead. It uses a different protein carrier and a lower concentration per unit, which means a higher unit count is used per area. The per-unit price is lower, and total treatment costs are generally similar across brands once the unit count is accounted for. Many patients notice a fast onset, often within two to three days.
Notable for
- Slightly broader spread — well suited for wide forehead treatment
- Fast onset, often 2–3 days
- Lower per-unit price (higher units used per area)
- Galderma Aspire loyalty program
Some patients prefer this if
Your injector recommends it for broader treatment areas like the forehead, or if you want a fast onset and have responded well to it in the past.
Jeuveau
Built exclusively for aesthetics — known as "Newtox"
Onset
2–5 days
Duration
Typically 3–4 months
Spread
Comparable to Botox
Loyalty
Evolus Rewards ($40 off per treatment)
Pricing at RELUXE
$12 per unit
$9.50/unit for members
Jeuveau was designed from the ground up for cosmetic use only — it has no medical indications, which allowed Evolus to focus its entire clinical development program on aesthetic outcomes. Nicknamed "Newtox," it uses a manufacturing process called Hi-Pure technology and has a comparable safety and efficacy profile to established brands in clinical studies. The Evolus Rewards program offers $40 off per treatment, which makes it an appealing option for patients focused on value without sacrificing quality.
Notable for
- Designed exclusively for aesthetic treatment
- Fast onset for many patients
- Evolus Rewards: $40 off every treatment
- Competitive member pricing at RELUXE
Some patients prefer this if
Value is a meaningful consideration, or you want to explore a newer brand with a strong aesthetic-focused clinical background. The Evolus Rewards savings add up quickly for regular maintenance patients.
Daxxify
The first peptide-powered neurotoxin — may last longer for some patients
Onset
2–4 days
Duration
Up to 4–6 months in clinical trials
Spread
Comparable to Botox
Loyalty
Aspire Rewards (Galderma)
Pricing at RELUXE
$7 per unit
$5/unit for members
Daxxify is the first neurotoxin to use a peptide as its stabilizing carrier instead of human serum albumin (a protein derived from human blood). This makes it the first albumin-free neurotoxin available in the U.S. In clinical trials, Daxxify showed a median duration of approximately 6 months, with some patients maintaining results up to 9 months — longer than what is typically seen with other brands. Results still vary by individual and the area treated, but for patients who find themselves scheduling touch-ups more frequently, it may be worth discussing.
Notable for
- First albumin-free, peptide-stabilized neurotoxin
- May last longer for some patients (up to 6 months in trials)
- Fast onset, typically 2–4 days
- Could mean fewer maintenance appointments per year
Some patients prefer this if
Fewer appointments per year is appealing to you, or you have found that other neurotoxins seem to wear off faster than expected. Your injector can help assess whether Daxxify is a good fit based on your history.
Side by Side
Wrinkle Relaxer Comparison
A quick-reference overview. Duration figures reflect typical ranges — individual results vary. Dysport pricing appears lower per unit because more units are required per treatment area; total treatment costs across brands are often similar.
| Brand | Onset | Duration | Spread | FDA Since | Pricing at RELUXE | Loyalty |
|---|---|---|---|---|---|---|
| Botox | 3–7 days | Typically 3–4 mo. | Precise | 2002 | $280 foundation · $9–$10/unit | Allē Rewards |
| Dysport | 2–5 days | Typically 3–4 mo. | Slightly broader | 2009 | $4.00–$4.50/unit | Aspire (Galderma) |
| Jeuveau | 2–5 days | Typically 3–4 mo. | Comparable to Botox | 2019 | $12/unit · $9.50 member | Evolus Rewards ($40 off) |
| Daxxify | 2–4 days | Up to 4–6 mo. (trials) | Comparable to Botox | 2022 | $7/unit · $5 member | Aspire (Galderma) |
Member pricing reflects RELUXE VIP Membership. Duration and results vary by individual. Final pricing confirmed at consultation.
Transparent Pricing
How Foundation Pricing Saves You More
Most med spas charge a flat per-unit rate — every unit costs the same whether you need 20 or 80. At RELUXE, our Foundation model gives you a bundled starting dose at a set price, then additional units at a significantly lower rate. The more you need, the more you save.
At Our Most Popular Doses
| Brand | Popular Dose | Flat Rate Elsewhere | RELUXE Price | You Save |
|---|---|---|---|---|
| Botox® | 64 units | $896 | $676 | $220 |
| Jeuveau® | 50 units | $600 | $380 | $220 |
| Dysport® | 100 units | $500 | $375 | $125 |
| Daxxify® | 100 units | $700 | $520 | $180 |
* "Flat rate elsewhere" reflects typical Indiana market pricing: Botox $14/unit, Jeuveau $12/unit, Dysport $5/unit, Daxxify $7/unit. RELUXE pricing shown for new patients. Jeuveau price includes $40 Evolus Rewards rebate.
Add Areas, Save Even More
Many patients add masseters (jawline slimming), lower face, or platysmal bands (neck) to their treatment. Because those additional units are all at the discounted rate — not the foundation price — the savings grow significantly.
| Example Treatment | Total Units | Flat Rate | RELUXE Price | You Save |
|---|---|---|---|---|
| Botox full face + masseters | 89 units | $1,246 | $901 | $345 |
| Jeuveau full face + masseters | 75 units | $900 | $530 | $370 |
| Botox full face + platysmal bands | 84–104 units | $1,176–$1,456 | $856–$1,036 | $320–$420 |
| Dysport full face + masseters | 140 units | $700 | $495 | $205 |
* Unit estimates are typical ranges. Masseters typically require 20–25 additional Botox units or 40 Dysport units. Platysmal bands typically require 20–40 units. Your provider will recommend your exact dose during a free consultation.
How It Works
Foundation Dose
Start with a set number of units at a bundled price — this covers most standard treatment areas.
Additional Units
Need more? Each additional unit is heavily discounted vs. the flat rate you'd pay elsewhere.
Add Areas & Save
Add masseters, platysmal bands, or other areas — all at the lower additional-unit rate.
Your injector will recommend the right brand and dose during your free consultation. See full pricing details on our specials page.
Finding Your Fit
How to Think About Choosing
There is no wrong choice among these four brands. Think of these as considerations — not a decision checklist. Your injector will factor in your anatomy, muscle strength, goals, budget, and preferences to make a specific recommendation for your face.
If
You've used one brand for years and love it
There's no reason to switch. Consistency with a brand you know well — at a provider who knows your face — is a perfectly good approach.
If
Fewer appointments per year matters to you
Ask your injector about Daxxify. It may last longer for some patients, which could mean two or three visits per year instead of three or four.
If
You want to maximize loyalty program savings
Jeuveau's Evolus Rewards program offers $40 off every treatment. For regular maintenance patients, that adds up meaningfully over time.
If
You're treating a large forehead area
Your injector may suggest Dysport. Its slightly broader diffusion pattern can work well for wide, flat muscle groups and may require fewer injection points.
If
You want the longest clinical track record
Botox has over 20 years of post-market safety data and the broadest body of clinical research of any neurotoxin. Some patients find that reassuring.
If
You're trying tox for the first time
Your injector will recommend whichever brand makes the most sense for your anatomy and goals. You don't need to arrive with a preference.
You do not pick a brand. You book a consultation.
Your injector maps your facial movement, considers your goals, and recommends the right wrinkle relaxer for your face at that appointment. You can share preferences — and your injector will factor them in.
The Experience
What to Expect at Your Appointment
01
Free consultation and facial mapping
Your injector at RELUXE reviews your goals and watches your full range of facial movement. They assess muscle strength, symmetry, and the areas you want to address. Brand and dose are recommended based on this — not a menu.
02
Brand recommendation
Your injector will recommend one of the four brands — or confirm your preference if you have one — and explain the reasoning. This is a conversation, not a prescription. Questions are welcome.
03
Treatment — 15 to 30 minutes
The injection itself is quick. Small, precise doses are placed in targeted muscles. Most patients describe the sensation as a mild pinch. No numbing cream is required, though it can be requested.
04
Results and follow-up
You can return to normal activities immediately. Results begin appearing within a few days and reach their full effect around the two-week mark. A follow-up is available at two weeks for any fine-tuning.
Before your appointment
- ·Avoid blood thinners and alcohol for one week prior
- ·Discontinue retinoids two to three days before treatment
- ·Arrive with clean skin, no makeup in the treatment area
- ·Eat a light meal beforehand
After your appointment
- ·Avoid lying flat or vigorous exercise for four hours
- ·Do not rub or massage the treated area for 24 hours
- ·Avoid saunas and excessive heat for 48 hours
- ·Plan your two-week check-in for any fine-tuning
Common Questions
Frequently Asked Questions
Explore Further
Service pages, comparisons, and pricing
Dive deeper into any brand, or go straight to a head-to-head comparison.
Related Guides
Service Pages
Head-to-Head Comparisons
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