Can I use this with other vitamin B3 products?

Yes, but start slowly. This contains 5% niacinamide, so if using other B3 products, alternate days initially to assess tolerance. Most patients can build up to daily use of multiple B3 products.

Will this help with redness and sensitivity?

Absolutely. Niacinamide is clinically proven to reduce inflammation and strengthen barrier function, making it excellent for sensitive or reactive skin. Many patients see reduced redness within 2-4 weeks of consistent use.

How does this compare to other SkinCeuticals moisturizers?

Metacell Renewal B3 is unique because it combines moisturizing with active anti-aging ingredients. It's lighter than Triple Lipid Restore but more treatment-focused than basic hydrators like Hydrating B5 Gel.

Can I use this if I'm already using retinoids?

Yes, this is actually an excellent companion to retinoid treatments. The niacinamide helps counteract potential dryness and irritation from retinoids while the peptides support skin renewal. Apply this moisturizer after your retinoid product.

Metacell Renewal B3 — SkinCeuticals

Name: Metacell Renewal B3
Brand: SkinCeuticals
Availability: InStock

About Metacell Renewal B3

Metacell Renewal B3 is a comprehensive daily moisturizer that combines 5% niacinamide (vitamin B3) with a unique tri-peptide complex to target multiple signs of aging. This clinically-tested formula strengthens the skin's natural barrier function while improving skin texture, tone, and elasticity. The lightweight cream contains kakadu plum extract (one of the richest sources of vitamin C) and peptides that work synergistically to stimulate cellular renewal and collagen production. Regular use reveals smoother, more resilient skin with improved radiance and reduced appearance of fine lines. This 50ml formulation is ideal for patients seeking comprehensive daily care that addresses barrier function, hydration, and anti-aging concerns simultaneously.

Key Ingredients

5% Niacinamide (Vitamin B3)Tri-Peptide ComplexKakadu Plum ExtractSodium Hyaluronate

How to Use

Apply twice daily after cleansing and serums. In the morning, dispense a pearl-sized amount and gently massage into face and neck, followed by sunscreen. In the evening, apply as your final moisturizing step. Can be layered under heavier creams if additional hydration is needed. Allow 2-3 minutes for full absorption before applying makeup.

Pro Tip from Our Clinicians

This cream works exceptionally well as a recovery moisturizer after chemical peels or microneedling treatments at RELUXE. The niacinamide helps calm post-procedure irritation while the peptides support healing. Start with evening application only for the first week after treatments.

Best For Skin Types

normaldrycombinationsensitive

Targets

fine linestexturedullnessbarrier damagedrynessredness

Pairs Well With

peels skinpen hydrafacial

Metacell Renewal B3

About Metacell Renewal B3

Key Ingredients

How to Use

Best For Skin Types

Targets

Pairs Well With

Frequently Asked Questions

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