Discoloration Defense

Discoloration Defense is a multi-pathway pigment-correcting serum by SkinCeuticals that targets stubborn dark spots, post-inflammatory hyperpigmentation, and melasma at multiple stages of melanin production. The formula combines 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES to inhibit melanin synthesis, reduce melanin transfer, and accelerate cell turnover simultaneously—a comprehensive approach that delivers visible improvement in discoloration where single-ingredient products fail. Available exclusively at RELUXE Med Spa in Westfield and Carmel, Indiana. Pigment disorders are among the most frustrating skin concerns because they're triggered by so many factors—UV exposure, hormones, inflammation, and heat. Indiana's strong summer sun and seasonal shifts make pigmentation especially persistent for Hamilton County residents. Discoloration Defense was formulated to address this complexity with a four-ingredient approach that works at every step of the pigmentation pathway. Tranexamic acid reduces UV-triggered melanin signals. Kojic acid inhibits the tyrosinase enzyme that produces melanin. Niacinamide blocks melanin transfer to the skin surface. HEPES accelerates cell turnover to shed pigmented cells faster. Together, they produce measurable lightening of dark spots within 6-12 weeks—and the improvement compounds with continued use. Our RELUXE providers pair Discoloration Defense with daily mineral SPF, periodic IPL or chemical peels, and Colorescience Even Up for the most complete pigment management protocol available.